Application of the Optical Method in Experimental Cardiology: Action Potential and Intracellular Calcium Concentration Measurement

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Authors	RONZHINA Marina ČMIEL V. JANOUŠEK Oto KOLÁŘOVÁ Jana NOVÁKOVÁ Marie BABULA Petr PROVAZNIK Ivo
Year of publication	2013
Type	Article in Periodical
Magazine / Source	Physiological Research
MU Faculty or unit	Faculty of Medicine
Citation
Field	Physiology
Keywords	Optical method; Fluorescent dyes; Action potential; Calcium concentration
Attached files	novakova.pdf
Description	It has been shown that, in addition to conventional contact electrode techniques, optical methods using fluorescent dyes can be successfully used for cardiac signal measurement. In this review, the physical and technical fundamentals of the method are described, as well as the properties of the most common systems for measuring action potentials and intracellular calcium concentration. Special attention is paid to summarizing limitations and trends in developing this method.
Related projects:	Informační technologie v biomedicínckém inženýrství