Application of the Optical Method in Experimental Cardiology: Action Potential and Intracellular Calcium Concentration Measurement

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Authors

RONZHINA Marina ČMIEL V. JANOUŠEK Oto KOLÁŘOVÁ Jana NOVÁKOVÁ Marie BABULA Petr PROVAZNIK Ivo

Year of publication 2013
Type Article in Periodical
Magazine / Source Physiological Research
MU Faculty or unit

Faculty of Medicine

Citation
Field Physiology
Keywords Optical method; Fluorescent dyes; Action potential; Calcium concentration
Attached files
Description It has been shown that, in addition to conventional contact electrode techniques, optical methods using fluorescent dyes can be successfully used for cardiac signal measurement. In this review, the physical and technical fundamentals of the method are described, as well as the properties of the most common systems for measuring action potentials and intracellular calcium concentration. Special attention is paid to summarizing limitations and trends in developing this method.
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