miR-17-5p Regulates Endocytic Trafficking through Targeting TBC1D2/Armus

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Authors	SERVA Andrius KNAPP Bettina TSAI Yueh-Tso CLASS Christoph LISAUSKAS Tautvydas MATULA Petr HARDER Nathalie KADERALI Lars ROHR Karl ERFLE Holger EILS Roland BRAGA Vania STARKUVIENE Vytaute
Year of publication	2012
Type	Article in Periodical
Magazine / Source	PLoS One
MU Faculty or unit	Faculty of Informatics
Citation
Doi	http://dx.doi.org/10.1371/journal.pone.0052555
Field	Use of computers, robotics and its application
Keywords	Cancer cell-proliferation; epidermal-grow-factor; endosomal traficking; application of image analysis
Description	We have developed an image analysis approach for segmentation and classification of cell nuclei that was used in a study of the regulation of endocytic trafficking. A novel function of miR-17 was discovered, which might act cooperatively with other functions of miR-17 and related miRNAs in health and disease.
Related projects:	Dynamika a organizace chromosomů během buněčného cyklu a při diferenciaci v normě a patologii