Nové technologie a perspektivy analýzy metabolomu embrya

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Title in English The new technologies for the analytical examination of the embryonic metabolome and its prospects
Authors

CRHA Igor MÁDR Aleš MUSILOVÁ Jindra GLATZ Zdeněk ŽÁKOVÁ Jana VENTRUBA Pavel

Year of publication 2012
Type Article in Periodical
Magazine / Source Česká gynekologie
MU Faculty or unit

Faculty of Medicine

Citation
Field Gynaecology and obstetrics
Keywords metabolomics; metabolome analysis; capillary electrophoresis; embryo; assisted reproductive techniques
Attached files
Description Nowadays, very sensitive analytical technologies are available. They enable exact measurement of various molecules – products of embryo metabolism during first days of cultivation. The capillary electrophoresis is one of promising method. Recent studies analysed metabolic differences between embryos that result in a pregnancy and those that do not. Amino acid levels, glucose or pyruvate in the embryo culture media were analysed most frequently. However, results of these studies are ambiguous.
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