CITP in clinical analysis
| Authors | |
|---|---|
| Year of publication | 2012 |
| Type | Article in Proceedings |
| Conference | Book of Abstracts of CECE 2012 (9th International Interdisciplinary Meeting on Bioanalysis) |
| MU Faculty or unit | |
| Citation | |
| Field | Analytic chemistry |
| Keywords | capillary isotachophoresis; clinical analysis; biominerals |
| Description | A method for the analysis of renal stones by capillary isotachophoresis (CITP) with conductometric detection was developed when the qualitative and quantitative analysis of organic compounds (urate, oxalate) and inorganic ions (phosphate, Ca2+, Mg2+, Na+, NH4+) species commonly present in mixed renal stones in three separate steps can be carried out with limits of detection about 10 mikromol.L-1. The developed method was validated by the analysis of real samples and can also be employed for the determination of the above mentioned analytes in some other samples (bones, teeth) concerning apatite biominerals (fluoro-, carbonate-, chloro-apatite). In addition, this method can be used also for the analysis of biofluids (urine). |
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