CITP in clinical analysis

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Authors

JAROLÍMOVÁ Zdeňka LUBAL Přemysl KANICKÝ Viktor

Year of publication 2012
Type Article in Proceedings
Conference Book of Abstracts of CECE 2012 (9th International Interdisciplinary Meeting on Bioanalysis)
MU Faculty or unit

Faculty of Science

Citation
Field Analytic chemistry
Keywords capillary isotachophoresis; clinical analysis; biominerals
Description A method for the analysis of renal stones by capillary isotachophoresis (CITP) with conductometric detection was developed when the qualitative and quantitative analysis of organic compounds (urate, oxalate) and inorganic ions (phosphate, Ca2+, Mg2+, Na+, NH4+) species commonly present in mixed renal stones in three separate steps can be carried out with limits of detection about 10 mikromol.L-1. The developed method was validated by the analysis of real samples and can also be employed for the determination of the above mentioned analytes in some other samples (bones, teeth) concerning apatite biominerals (fluoro-, carbonate-, chloro-apatite). In addition, this method can be used also for the analysis of biofluids (urine).
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