Project information
National Institute of Virology and Bacteriology
(NIVB)
- Project Identification
- LX22NPO5103
- Project Period
- 6/2022 - 12/2025
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- national recovery plan
- 5.1 EXCELES
- MU Faculty or unit
-
Central European Institute of Technology
- prof. RNDr. Robert Vácha, PhD.
- Mgr. Gabriel Demo, Ph.D.
- Mgr. Martina Drabinová
- Francesco Luca Falginella, Ph.D.
- Ing. Tibor Füzik, Ph.D.
- Mgr. Mária Gondová
- Ing. et Ing. Miroslav Haman
- Mgr. Adelheid Hanáčková
- Ing. Ondřej Kroutil, Ph.D.
- Timothée Emmanuel Jonathan Rivel, Ph.D.
- Mgr. Jana Salamonová
- prof. RNDr. Robert Vácha, PhD.
- Other MU Faculty/Unit
- Faculty of Medicine
- Other MU Faculty/Unit
-
Faculty of Science
- prof. RNDr. Roman Pantůček, Ph.D.
- Mgr. Tibor Botka, Ph.D.
- Lenka Buňatická
- prof. RNDr. Jiří Doškař, CSc.
- Mgr. Adéla Finstrlová, Ph.D.
- Mgr. Jiřina Havránková
- Mgr. Vojtěch Kovařovic, Ph.D.
- Mgr. Lucie Kuntová, Ph.D.
- Mgr. Ivana Mašlaňová, Ph.D.
- Mgr. Michal Zeman, Ph.D.
- Cooperating Organization
-
Institute of Microbiology of the ASCR, v. v. i.
Institute of Molecular Genetics of the ASCR, v. v. i.
Institute of Organic Chemistry and Biochemistry of the ASCR, v. v. i.
- Responsible person RNDr. PhDr. Zdeněk Hostomský, CSc.
Palacký University, Olomouc
Prague Institute of Chemical Technology
Biological Centre of the ASCR, v. v. i.
Basic and oriented or clinical research on viruses and pathogenic bacteria is essential to understand the processes by which they cause disease, how they escape the immune system and how they can resist treatment. Therefore, research activities at the National Institute of Virology and Bacteriology will focus on characterizing pathogens causing existing and emerging infectious diseases, describing virus and bacteria interactions with the host, understanding the molecular mechanisms of pathogenesis, and developing antiviral and antibacterial agents and vaccines. Individual research groups will work on viruses and bacteria causing diseases with significant health and economic impact, including HIV-1, influenza, tick-borne encephalitis, hepatitis B, SARS-CoV-2, enteroviruses, and the bacteria B. pertussis, S. aureus, and T. pallidum. By working with pathogens that are relevant to current clinical practice, the research groups will have the expertise and equipment for the ongoing study of new pathogens that could become prevalent in the human population in the future.
Sustainable Development Goals
Masaryk University is committed to the UN Sustainable Development Goals, which aim to improve the conditions and quality of life on our planet by 2030.
Publications
Total number of publications: 117
2022
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HOW LARGE MOLECULES CAN ENTER CELL
Year: 2022, type: Conference abstract
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CHARACTERIZATION OF ESCHERICHIA COLI ISOLATES FROM PATIENTS WITH COLON CANCER
Year: 2022, type: Conference abstract
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Interaction of therapeutic kayvirus phage with Staphylococcus aureus on transcriptomic level
Year: 2022, type: Conference abstract
-
Magainin 2 and PGLa in bacterial membrane mimics IV: Membrane curvature and partitioning
BIOPHYSICAL JOURNAL, year: 2022, volume: 121, edition: 23, DOI
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MINION AS A TOOL FOR SEQUENCING OF VARIABLE AND PARALOGOUS GENOMIC LOCI OF TREPONEMA PALLIDUM
Year: 2022, type: Conference abstract
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Phage-mediated bacterial lysis studied by AFM and SPR
Year: 2022, type: Appeared in Conference without Proceedings
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Polyelectrolyte coating of cryo-EM grids improves lateral distribution and prevents aggregation of macromolecules
Acta Crystallographica Section D: Structural Biology, year: 2022, volume: 78, edition: NOV, DOI
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Rather die than be taken by the phage: Staphylococcus aureus prophage immunity protein protects population against kayviruses
Year: 2022, type: Conference abstract
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STRUCTURAL CHARACTERISATION OF VIRUS REPLICATION IN SITU
Year: 2022, type: Conference abstract
-
Structure of Human Enterovirus 70 and Its Inhibition by Capsid-Binding Compounds
Journal of Virology, year: 2022, volume: 96, edition: 17, DOI